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  • Dear Redaer
    cord lesion are restricted in their mobility and quality of life in spite of intensive movement therapy or applied direct electric stimulation Several studies indicate that repetitive transcranial magnetic stimulation rTMS decreases the spasticity and central pain after spinal cord lesion and that repetitive sessions of rTMS may induce movement in the paretic legs and promote the recovery of normal voiding function of the bladder The improvement caused by rTMS

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_17.htm (2016-05-02)
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  • Dear Redaer
    are sporadic but 5 10 are familial due in large part to mutations in superoxide dismutase 1 SOD1 ALS is characterized by upper and motor neuron loss In the light of its clinical heterogeneity there is still no unitary pathogenetic model of ALS The working hypothesis is that ALS may be caused by a complex interplay between genetic and environmental factors Several lines of evidence favour glutamate driven excitotoxicity as one of the most likely pathogenic mechanisms of ALS At the moment there is no established therapy for ALS and the anti glutamatergic compound riluzole is the only approved drug for ALS Riluzole is safe but its effect is limited to prolongation of median survival by 2 3 months This poor therapeutic effect underlines the need for new potential treatments in ALS Repetive transcranial magnetic stimulation rTMS might theoretically be beneficial in ALS for two reasons rTMS may modulate motor cortex excitability and reduce glutamate induced excitotoxicity rTMS can also increase the expression of neurotrophic factors which could counteract the neuronal damage in ALS In very recent years three controlled pilot studies explored the effect of rTMS in the treatment of ALS These studies showed that rTMS might reduce the

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_18.htm (2016-05-02)
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  • Dear Redaer
    potential treatment tool in clinical trials involving psychiatric patients In this chapter all the rTMS clinical studies of obsessive compulsive OCD and schizophrenia disorders were reviewed In particular only five studies have employed rTMS in the treatment of OCD patients showing disappointing as well as encouraging findings Indeed while the majority of patients did not benefit from rTMS treatment there is some evidence that high frequency 10 Hz rTMS of the right prefrontal cortex as well as 1 Hz rTMS of premotor cortex was effective in temporarily reducing compulsive behaviors and obsessive symptoms in a subgroup of OCD patients On the other hand several studies have treated schizophrenics with rTMS The most promising findings were an improvement of negative symptoms after 2 weeks of high frequency 10 Hz rTMS over the left prefrontal cortex and a reduction of unremitting auditory hallucinations with 1 Hz rTMS over the temporoparietal auditory cortex One of the main challenges in the interpretation of these studies was the lack of a reliable placebo sham condition Indeed the most commonly used sham condition involves tilting the coil 45 or 90 off the head in order to direct the magnetic field from the brain However it has

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_19.htm (2016-05-02)
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  • Dear Redaer
    last 12 years a considerable number of clinical research trials have investigated the potential use of rTMS methods in the treatment of patients with depressive disorders The majority of these trials have focused on the use of high frequency stimulation applied to the left dorsolateral prefrontal cortex DLPFC in patients with treatment resistant depression TRD Analysis of the results of this body of research indicates that this form of rTMS

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_20.htm (2016-05-02)
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  • Dear Redaer
    rTMS in the treatment of different neuropsychiatric diseases In this context brain stimulation techniques tailored to modulate individual plastic changes associated with neurological diseases might enhance clinical benefits and minimize adverse effects There is compelling evidence that rTMS causes changes in neuronal circuits as reflected by behavioral changes These alterations suggest regional changes in neurotransmitter release and that rTMS increases the secretion of neuroprotective molecules such as a brain derived

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_21.htm (2016-05-02)
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  • Dear Redaer
    uniroma1 it Abstract Repetitive transcranial magnetic stimulation rTMS is a non invasive valid tool to investigate mechanisms of cortical plasticity There is also evidence that rTMS is useful for treating a variety of neurological and psychiatric disorders However an increased risk of seizures and others undesirable effects such as pain or headache have been described Therefore guidelines for its safe use and study on the tolerability of rTMS have been developed The safety guidelines consider multiple rTMS parameters such as frequency intensity duration and site of stimulation that have shown to elicit seizures post stimulation activity or spread of activation 1 2 To date almost all major adverse effects such as seizures reported in literature occurred before the advent of current safety guidelines under parameters that retrospectively fall outside these recommended criteria A review of study therefore suggests that rTMS delivered at low frequency would be also applied for the treatment of epilepsy offering potential benefit with acceptable risk 3 Moreover the majority of studies which have used rTMS to treat psychiatric disorders or movement disorders such as Parkinson s disease within a range of stimulation parameters defined according to the safety guidelines have not been associated with major adverse

    Original URL path: http://www.neurorehab.hu/rtms/htm/ab_22.htm (2016-05-02)
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  • www.neurorehab.hu

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    Original URL path: /index.php?option=com_phocagallery&view=detail&catid=1:epuelet&id=5:epuelet-es-az-udvar&phocaslideshow=1&tmpl=component&Itemid=26 (2016-05-02)


  • www.neurorehab.hu

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    Original URL path: /index.php?option=com_phocagallery&view=detail&catid=1:epuelet&id=4:also-elter&phocaslideshow=1&tmpl=component&Itemid=26 (2016-05-02)